Zidovudine
- Subj. Area:
- V Medicine and Care
- Ger:
- Zidovudin
- Fr:
- zidovudine
- SN:
- Zidovudine is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA during reverse transcription; it improves immunologic function, partially reverses the HIV-induced neurological dysfunction, and improves certain other clinical abnormalities associated with AIDS; its principal toxic effect is dose-dependent suppression of bone marrow, resulting in anemia and leukopenia (based on MeSH-2009)
- RT:
-
AIDS
- Conc:
-
B: -
E: Zidovudine
I: zidovudine
M: Zidovudine (D015215)
